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The Nikkei 225 index closed up 1.21% at 39,849.14.The latest collection price of the heavy anticancer star drug Regofibril has dropped to a minimum of more than 4 yuan per tablet. The reporter learned at the scene of the tenth batch of drug collection that the anti-tumor drug Regofibril tablets with annual sales of more than 1 billion yuan have been auctioned by this collection, and the price has almost dropped to between 4 yuan and 6 yuan, which is 90% lower than the price limit. Nanjing Zhengda Tianqing is expected to win the bid in the first round of quotation. Regofibril can treat colorectal cancer, liver cancer and other cancers. Its original research manufacturer is Bayer, which occupies almost all the market share in China. The price of this collection is about 172 yuan per tablet. (science and technology innovation board Daily)In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for the replacement of generic drugs. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)

Deputy Prime Minister of Ukraine: We are ready to discuss the deployment of foreign troops in our own territory. On December 12, local time, the reporter of the General Desk learned that Ukrainian Deputy Prime Minister Stefani Hina said that Ukraine is ready to discuss the deployment of foreign troops in its own territory. It is reported that French President Macron and Polish Prime Minister Tusk plan to exchange views on the deployment of about 40,000 peacekeepers in Uzbekistan on the 12th. (CCTV News)Interbank certificates of deposit funds are popular. In the context of the current downward trend of non-bank interbank deposit rates, interbank deposit rates are relatively more attractive, and interbank deposit funds have recently gained popularity. Since December, the 7-day holding fund of AAA index of China Securities Interbank Deposits issued by BlackRock Fund and Agricultural Bank of China Credit Suisse Fund has reached the upper limit of 5 billion yuan, and triggered proportional placement. Both funds are partially confirmed by the principle of "doomsday ratio confirmation", and the doomsday confirmation ratio is 73.36% and 27.02% respectively. In addition, Huatai Bairui Fund and China-Canada Fund also imposed subscription restrictions on their 7-day holding funds of the AAA Index of China Securities Interbank Deposits. From December 11th, the amount of multiple cumulative subscriptions (including conversion and fixed investment) for a single fund account of Huatai Bairui CSI Interbank Deposit Certificate AAA Index 7-day holding fund shall not exceed 100,000 yuan; From December 6th, the subscription amount of a single investor of the 7-day holding fund of China-Canada CSI Interbank Deposit Certificate AAA Index will not exceed 10 million yuan (except for individual investors and public asset management products). (CSI Taurus)Hong Kong Stock Exchange: Before the end of 2025, the system will be technically compatible with the T+1 settlement cycle. The Hong Kong Stock Exchange announced on December 12 that it will launch a plan to improve the post-trading service of the stock spot market. Starting from mid-2025, the Hong Kong Stock Exchange will gradually introduce new post-trading functions on its OCP. The new functions include automatic report downloading and information exchange, real-time transmission and processing of transaction data, related positions and reference data, and real-time delivery instruction pairing. As part of the whole platform upgrade plan, HKEx will ensure that its system is technically compatible with the T+1 settlement cycle by the end of 2025. However, what kind of settlement cycle will be adopted in Hong Kong in the future will be decided after market discussion.

Treasury futures turned green for 30 years, and treasury futures turned down. The 30-year main contracts turned green and fell by 0.03% to 116.94. The 10-year main contract was reported at 108.17, and the increase narrowed to 0.02%.Polls show that the support rate of Japanese Prime Minister Shi Pomao's cabinet has dropped to 26.8%. According to a report by the Japan News Agency on the 12th local time, the poll conducted by the agency in December showed that the support rate of Shi Pomao's cabinet was 26.8%, down 1.9 percentage points from last month. (CCTV News)South Korea's National Assembly passed "Yin Xiyue's General Special Inspection Law" and "Jin Jianxit's Inspection Law". The reporter of the General Station was informed that on the 12th local time, South Korea's National Assembly held a general meeting of parliamentarians and passed "Yin Xiyue's General Special Inspection Law" and "Jin Jianxit's Inspection Law". (CCTV News)